© 2014, Copyright the Authors Journal compilation © 2014, The American Geriatrics Society. Individuals with MCI with a low MoCA-TS and a low newly devised memory index score (MoCA-MIS) are at greater risk of short-term conversion to AD.Īlzheimer Memory Index Score Montreal Cognitive Assessment mild cognitive impairment. Identifying individuals with MCI at high risk of conversion to AD is important clinically and for selecting appropriate subjects for therapeutic trials. Individuals with multiple-domain amnestic MCI had the highest AD conversion rates (73.9%). One hundred fourteen participants progressed to AD (MCI-AD), and 51 did not (nonconverters MCI-NC) 90.5% of participants with MCI with a MoCA-TS less than 20/30 and a MoCA-MIS less than 7/15 at baseline converted to AD within the average follow-up period of 18 months, compared with 52.7% of participants with MCI above the cutoffs on both scores. Individuals meeting Petersen's MCI criteria (N = 165).īaseline MoCA scores at MCI diagnosis were collected from charts of eligible individuals with MCI, and MoCA-TS, MoCA-MIS, and a cognitive domain index score were calculated to assess their prognostic value in predicting conversion to AD. Alternating Trail Making: Administration: The examiner instructs the subject: 'Please draw a line, going from a number to a letter in ascending order. ![]() ![]() The total possible score is 30 points a score of 26 or above is considered normal. To assess the usefulness of the Montreal Cognitive Assessment (MoCA) total score (MoCA-TS) and Memory Index Score (MoCA-MIS) in predicting conversion to Alzheimer's disease (AD) in individuals with mild cognitive impairment (MCI). administer the MoCA is approximately 10 minutes.
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